Abstract:OBJECTIVE:To report a rare chronic inflammatory disorder, eosinophilic lymphoid granuloma (ELG), in head and neck with literature review. METHODS:Clinical and pathological data of four cases of ELG was studied retrospectively. Literature was reviewed. RESULTS:Of all the 4 cases, they were two male and two female, ages 14~43. The typical clinical manifestation was periauricular and/or neck masses and was concomitant with periphreal eosinophilia. All the cases underwent surgical excision. Pathological examination showed marked infiltration of eosinophil and lymphocyte with germinal centers, proliferation of blood vessel, and thick fibrosis. One case received postoperative radiotherapy. Two cases underwent operation two or three times because of recurrence. CONCLUSION:ELG possesses typical clinical and pathological characteristics and needs comprehensive treatment.