OBJECTIVE:To investigate the therapeutic effect of endoscopic vadian neurectomy on vasomotor rhinistis. METHODS:Vadian neurectomy under nasal endoscope was carried out on 45 patients with vasomotor rhinistis, and “Rhino conjunctivtis quality of life questionnaire (RQLQ)” was used for measuring the scores of life quality of patients both preoperatively and 4 years postoperatively. RESULTS:Four years after operation, evaluation according to the Chinese traditional symptom scoring system showed that 37 of 45 cases (88.2%) got complete response, 4 cases (8.9%) partial response, and 4 cases (8.9%) were ineffective. RQLQ assessment showed that nasocular and nonnasocular symptoms, daily life and sleep quality, emotional state were significantly improved after operation; the ability to solve practical problems was also significantly increased. Among the symptoms of rhinoconjunctivitis, sneezing and waterrhinorhea were most significantly improved. Compared with the total preoperative score of questionnaire, the score 4 years postoperatively decreased more than 50% in 39 cases (86.7%), and decreased less than 20% in only 3 cases (6.7%). CONCLUSION:The vadian neurectomy through nasal cavity under the nasal endoscope is an effective and safe technique for vasomotor rhinitis.