Abstract: Objective To study the diagnosis and treatment of submucosal laryngeal carcinoma and to improve the clinical efficacy. Methods Clinical data of 8 cases of submucosal laryngeal carcinoma admitted to our hospital from 1999 to 2007 was analyzed retrospectively. Results Spaceoccuping lesions were observed by neck CT scan in all cases and the diagnosis was confirmed by submucosal biopsy. All patients received neck dissection and total laryngectomy. Conclusion Neck CT examination and biopsy of submucosal tissue are important for the diagnosis of submucosal laryngeal caarcinoma. Extended resection is essential for a better curative effect.