Objective To study methods to improre the intranasal endoscopic dacryocystorhinostomy. Methods 181 Patients with chronic dacryocystitis, treated with endoscopic dacryocystorhinostomy, were randomly divided into three groups. In the silver clip+PVF group (60 cases), silver clips were used for fixing the mucous membrane flap of lacrimal sac to that of nasal cavity at the leading edge of uncinate process, and PVF medical sponge was used to support the lacrimal sac cavity. In the PVF group (62 patients), PVF medical sponge was used for supporting the lacrimal sac cavity. In the silver clip group (59 cases), silver clips were used to fix the mucous membrane flap of lacrimal sac to that of nasal cavity in front of the uncinate process. Results Three months after operation, the cure rates of the silver clip+PVF group, PVF group and silver clip group were 93.94%, 82.09% and 79.69% respectively. The satisfaction of the patients were (82.26±11.00) points, (76.76±10.565) points and (73.78±9.991 ) points. Conclusion Combined application of silver clip and PVF medical sponge can significantly improve the successful rate of the endoscopic dacryocystorhinostomy.