目的 探讨青少年突发性耳聋的临床特点、疗效及预后。方法 选取65例青少年突发性耳聋病例作为研究对象，根据患者性别、患侧耳、发病季节、听力图形、听力下降程度、就诊时间、有无伴眩晕、耳鸣、吸烟饮酒史等进行分组，所得数据采用单因素秩和检验，分别比较各组治疗有效率的差异，并用logistic多元回归分析法评价各相关因素对预后的影响。结果 治疗后总有效率为58.5%；单因素分析显示就诊时间、听力下降程度、有无伴眩晕等因素与预后有关（P<0.05）；多因素logistic回归分析中发病至就诊时间、有无伴眩晕与预后有相关性（P<0.05）。结论 在影响青少年突发性耳聋预后的因素中，眩晕、听力损失程度及就诊时间与预后有关。
Abstract: Objective To study the causes, clinical characteristics, treatment efficacy, and main affecting factors in the prognosis of sudden deafness in juveniles. Methods 65 patients with sudden deafness were chosen and divided into different groups according to sex, nationailty ill ear, season, audiogram, degree of hearing loss, beginning time of therapy, accompanying vertigo or not, tinnitus, smoking and drinking history, and so on. The rank sum test and logistic regression analysis were then used for analyzing the data. Results Of all the 65 patients, the therapeutic effective rate was 58.5%. Single factor analysis showed that the beginning time of therapy, degree of hearing loss, accompanying vertigo were correlated with the prognosis (P<0.05). The logistics regression analysis showed that the beginning time of therapy and accompanying vertigo were correlated with patients’ prognosis (P<0.05). Conclusion The prognosis of sudden deafness in juveniles is related with the beginning time of therapy, accompanying vertigo and degree of hearing loss,which is similar to those of adults but also with some special characteristics.
努尔比亚·米尔扎木 刘志连 亚力坤·亚生 王淑霞.青少年突发性耳聋预后相关因素分析[J].中国耳鼻咽喉颅底外科杂志,2011,17(6):450-453复制