Abstract:Objective To investigate the effects of obstructive sleep apnea hypopnea syndrome (OSAHS) on the quality of life of the patients. Methods The quality of life was assessed with the Medical Outcomes study SF-36 Health Survey in 93 patients with OSAHS. Excessive Daytime sleepiness (EDS) was assessed with Epworth sleepiness scale (ESS). Pearson liner correlation were used for studying the association between each domain score of SF-36 Health Survey and patients information, PSG parameters Influences of age, gender, BMI (body mass index), EDS, and PSG parameters, EDS scores. Results Each domain of SF-36 had no significant difference in gender; four domains of SF-36 had correlation with age; five domains of SF-36 correlated with EDS; seven domains of SF-36 correlated between BMI and LSaO2 (lowest Oxygen saturation); six domains of SF-36 correlated with AHI (apnea hypopnea index). The result of SF-36 instrument showed the results that the disease had the effect on three dimensionalities such as physical functioning, general health perceptions and vitality, but less influenced bodily pain and social functioning. It also showed that integrated infective factors included EDS, BMI, LSaO2, and AHI. Conclusion Age, BMI, EDS score, LSaO2, AHI have a significantly effect on the OSAHS patients. BMI, EDS score, LSaO2, AHI have a significant side effect on the OSAHS patients. Applying instruments of life quality to assessing of the OSAHS patients, we can know about the physical, emotional and social functions. It can factually reflect the effect of the disease and treatment, when comprehensive rehabilitation approach is applied, psychological support and psychiatric aberration must be stressed to make the patients look on the disease correctly, amend bad mood, cooperate with doctors actively. The knowledge of the disease and the consciousness of self health care must be improved to fetch favorable psychologic diathesis, and enhance the patients'qulity of life.