Abstract:Objective To analysis the correlation between micrometastasis in cervical lymph node and early recurrence, and prognosis in patients with laryngocarcinoma of pN0 stage. Methods The clinical and pathological data of 31 patients suffering from laryngeal squamous cell carcinoma with pathologically negative node were analyzed retrospectively. The micrometastasis was detected with HE staining combined with semiconsecutive sectioning from the lymph node specimens after neck dissection operation. The chisquare test was used for analyzing the relationship between the micrometastasis and early recurrence, and KaplanMeier curve was used for describing the diseasefree survival curve. Results The correlation between micrometastasis and early recurrence was not significant (P>0.05). The diseasefree survival rate of the patients with and without micrometastasis had no obvious separation trend (P>0.05). Conclusion In patients with laryngocarcinoma of pN0 stage, the clinical and prognostic implications of micrometastasis could not be established.
