Objective To investigate the clinical efficacy of nasal endoscopic surgery for sinusitis and nasal polyps. Methods 1135 cases (2107 sides) of chronic sinusitis and nasal polyps were treated with ESS, and following up survey 1-3 year postoperatively, with an average of 1.2 years. Results It was found that 862 cases were cured (75.9%), 214 cases achieved symptonatic relief (18.9%), 59 cases remained failure (5.2%), and the effective rate was 94.8%, Postoperative complication incidence was about 1.6%, mainly was adhesion of nasal cavity. Conclusion The curative effect of ESS is successful. It is effective to use reasonable intraoperative controlled hypotension to reduce bleeding concentration, it is very important to treat middle turbinate precisionly, and regularly followingup could reduce operation complications.