Objective To explore to optimal treatment of aggressive fibromatosis in head and neck. Methods 12 patients with aggressive fibromatosis in head and neck underwent surgery, and 7 of them received radiotherapy. Results All of them were following up for 5 to 15 years. No one recurred in the 7 cases receiving surgery combined with postoperative radiotherapy, while the other 5 recurred with in 7 to 18 months after surgery. The total recurrence rate was 41.7%, and that with negtative surgical margins was 14.3%. 〖WTHZ〗Conclusion Acquirement of negative surgical margins can reduce the recurrence of aggressive fibromatosis in head and neck. But this tumor can hardly be excised thoroughly. Postoperative radiotherapy may be a preferred measure for reducing the recurrence rate.