Objective To investigate the relationship between laryngopharyngeal reflux and vocal cord polyps. Methods 15 patients with vocal cord polyps which diagnosed with postoperative pathological examination were recruited and performed 24hour dual probe pH monitoring from Mar.2010 to Mar 2011. All these patients signed informed consent. Results Of all the 15 patients, 6(40%) were found pH positive at larynx, 13(86.67%) at esophagus and 6(40%) at both. Among the 6 patients with laryngeal reflux, the case number of positive reflux symptom index (RSI) and reflux finding score (RFS) was 5 (83.33%) and 4 (66.67%) respectively. In the 13 patients with esophageal reflux, the case number of positive RSI and RFS was 9 (69.23%) and 11 (84.62%) respectively. Conclusion The reflux of upper gastrointestinal tract and laryngopharynx may play a certain role in the development of vocal cord polyps. As a stimulator, the gastrofeflux might be the direct or incentive cause for vocal cord polyps. And the stimulator of gastroreflux might be the direct or incentive cause for vocal cord polyps.