腮腺多发沃辛瘤临床回顾性分析
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陈杰,Email:cj1959@126.com.

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湖南省肿瘤医院青年科学基金项目(A201104)


Retrospective analysis of the multifocal Warthin’s tumor in parotid glands
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    目的分析腮腺多发沃辛瘤的临床特点并探讨其诊疗方法。方法 对收治的26例腮腺多发沃辛瘤患者的临床资料进行回顾性研究,对影响复发的因素采用Fisher’s 确切概率法进行分析,进而讨论该病适宜的治疗方式。结果26例腮腺多发沃辛瘤患者男女患病比率为2.25∶1,发病年龄45~81岁。细针穿刺细胞学检查(fine needle aspiration cytology, FNAC)诊断准确率为84.4%。其中2例保守治疗,1例放弃手术,余23例患者计29侧腮腺接受手术治疗。5例患者计6侧腮腺术后复发。分析患者年龄、性别、吸烟史、症状持续时间、肿瘤数目、直径、位置、伴发其他肿瘤、手术方式、手术并发症和术后吸烟情况对肿瘤复发的影响,手术方式是影响肿瘤复发的独立危险因素。结论腮腺多发沃辛瘤发病具有自身特点,细针穿刺细胞学检查是该病的常规检查,手术切除是主要的治疗方式。

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    ObjectiveTo study the diagnosis and treatment of multifocal Warthin’s tumor located in parotid glands via analyzing its clinical characteristics.MethodsClinical data of 26 patients suffering from multifocal Warthin’s tumor located in parotid glands and treated in our department from 1991 to 2010 was analyzed retrospectively. The proper treatment strategies were evaluated via Fisher’s exact propability univariate analysis about relapse of the tumor.ResultsIn the 26 cases, the male/female ratio was 2.25∶1, and their onset ages ranged from 45 to 81 years. The accuracy of fine needle aspiration cytology (FNAC) was 84.4%. 23 patients (29 sides) underwent surgical treatment and 5 cases (6 sides) recurred postoperatively. Age, sex, smoking history, duration of symptoms, number, diameter and location of tumors, synchronous tumors, surgical approach, operative complications and postoperative smoking were pooled and analyzed. The analytic results showed that surgical approach was the independent risk factor for the recurrence of the tumor.ConclusionsThe clinical features of multifocal Warthin’s tumor of parotid glands are characteristic. FNAC should be performed routinely to confirm the diagnosis and surgical resection of gland lobe is a reasonable manner to prevent or reduce relapse of the tumor.

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谢李 陈杰 黄文孝 包荣华 魏威 李晋芸 王俊琦 张海林.腮腺多发沃辛瘤临床回顾性分析[J].中国耳鼻咽喉颅底外科杂志,2013,19(3):213-216

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  • 在线发布日期: 2013-06-30
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