ObjectiveTo evaluate the efficacy of bilateral endoscopic vidian neurectomy on allergic rhinitis with bronchial asthma.Methods16 patients with allergic rhinitis and bronchial asthma received bilateral endoscopic vidian neurectomy. Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ), Visual Analogue Scale Questionnaire (VAS) and Asthma Quality of Life Questionnaire in Adult (AQLQ) were utilized to evaluate the quality of life before and after surgery.Results16 patients were followed up after surgery. Postoperative scores (±s) of RQLQ and VAS at the time of 6 months (0.79±0.43，2.51±1.60), 12 months (0.95±0.47，2.62±1.71), 24 months (1.35±0.50，2.79±1.73) were respectively lower than preoperative scores (2.23±0.48，7.33±1.15). Postoperative scores (±s) of AQLQ at the time of 6 months (4.01±0.60), 12 months (3.85±0.68), 24 months (3.66±0.75) were higher than preoperative scores (2.91±0.82). Their differences between postoperative and preoperative scores were statistically significant (P<0.01).ConclusionsBilateral endoscopic vidian neurectomy is an effective and safe technique in the treatment for patients with allergic rhinitis and bronchial asthma, which can effectively improve the quality of life of the patients.