ObjectiveTo investigate the skill and significance of middle turbinate processing in endoscopic sinus surgery.Methods80 patients with chronic sinusitis and nasal polyp were randomly divided into observation group (32 cases, 39 sides) and control group (48 cases, 54 sides). Protection of the spatial structure and morphology of middle turbinate was enhanced as much as possible during endoscopic sinus surgery in patients of the observation group, while the patients of the control group received traditional Messerklinger or Wigand surgery. Six months after surgery, the stability of the middle turbinate, the occurrence of stenosis or adhension of middle meatus, and the mucosal evaluation according to the LundKennedy endoscopic mucosal morphology scoring system between the two groups were compared.ResultsThe difference of preoperative LundKennedy scores between the two groups was statistically insignificant (t =1.659, P>0.05); 6 months after surgery, the score of the observation group (1.89±1.31) was much less than that of the control group(2.48±1.42) and the difference was statistically significant (t=8.1, P<0.01). In the patients of the observation group, the middle turbinate was stable, the occurrence rates of slight relocation, middle meatus stenosis and adhension were 83.2%, 4.1% and 6.7% respectively, while those of the control group were 44.9%, 21.6% and 10.3%. The differences of abovementioned rates between the two groups were statistically significant (χ2=10.77, P<0.01).ConclusionTo retain the relatively normal morphology and spatial structure of middle turbinate may be helpful to improve the clinical efficacy and to decrease the postoperative complications in endoscopic sinus surgery.