Objective To observe the influence of multiplanar staging surgery on carotid intimamedia thickness and metabolic index of patients with severe obstructive sleep apnea hypopnea syndrome (OSAHS) and metabolic syndrome (MS).Methods45 cases suffering from severe OSAHS with MS received multiplanar surgical treatment and were divided into effective group and ineffective group according to the therapeutic effect. Detection of blood total AHI、BMI、LSaO2、cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDLC), high density lipoprotein cholesterol (HDLC)、FBG、INS、ESS and polysomonography (PSG) monitoring was performed in all patients before operation and 12 months after treatment.ResultsBefore operation, the difference of apnea hypopnea index (AHI) between the two groups was significant (P<0.05), while those of age, BMI, LSaO2, LDLC, HDLC, CHOL, TG, FBG, INS, ESS and IMT were insignificant (P>0.05). 12 months after treatment, changes of AHI, LSaO2, CHOL, TG, LDLC, HDLC, INS, ESS and IMT were significant in both groups (P<0.05), except that of FBG (P>0.05). Comparison of abovementioned indexes before and 12 months after operation showed significant differences of IMT, ESS, AHI and LSaO2 in the effective group (P<0.05), and ESS and AHI in the ineffective group (P<0.05).ConclusionsMultiplanar surgery is effective for patients with severe OSAHS and MS. Positive surgical intervention of OSAHS may facilitate the treatment of MS. OSAHS may be an important factor in the development of MS. Surgical intervention of OSAHS may reverse or delay the process of carotid atherosclerosis.