Abstract:ObjectiveTo explore the clinical characteristics of solitary neurofibroma of nasal cavity to improve the diagnosis and treatment level.MethodsClinical data of 2 patients with solitary neurofibroma of nasal cavity was analyzed retrospectively, and related literature was reviewed.ResultsOf the 2 cases, the tumor was found occasionally in outpatient clinic due to stuffy nose. Soft tissue shadow and uneven enhanced mass were found by enhanced CT scan, with destruction and absorption of surrounding bone. Intraoperative detection showed the boundary of the tumor was clear, and endoscopic total resection was achieved. Pathologic examination showed numerous spindle cells with positive S100 staining. The symptoms got relieved in both cases after operation, and none recurred after 6 months followup.ConclusionsPeripheral nerve neurofibroma in nasal cavity has been rarely reported in literature. The definite diagnosis depends upon immunohistochemical staining. Total resection is the preferred method for the treatment of this tumor, and endoscopic surgery is the best choice.