下咽癌的外科治疗进展
作者简介:

刘良发,Email:liuliangfa301@163.com

基金项目:

北京教委面上项目(KM201510025026);北京友谊医院启动课题(yyqdkt2014-23);北京友谊医院导师启动课题 (yydszx2015-02)


Progress in surgical treatment for hypopharyngeal carcinoma
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    摘要:

    摘要:下咽恶性肿瘤占头颈部恶性肿瘤的5%左右。下咽鳞癌原发于梨状窝者占70%;其次是环后区,占15%~20%;最后是下咽后壁区,占10%~15%。下咽癌的治疗包括单纯放疗、单纯化疗、单纯手术或与放化疗手术相结合的综合治疗;以手术治疗为主的综合治疗仍是下咽癌的首选治疗手段。手术方式包括开放性手术和微创手术,开放性手术又分为保留喉功能的下咽癌切除与功能重建和全喉切除的下咽食管重建手术。微创手术包括经口CO2激光手术(transoral CO2 laser microsurgery, TLM)和经口机器人辅助下咽癌切除术。下咽部位的淋巴引流丰富,极易发生淋巴结转移,约50%的患者初次就诊时已出现颈部淋巴结转移,因此颈部淋巴结的处理已成为影响患者预后的关键。本文通过文献复习并结合临床经验,对下咽癌外科治疗的进展进行阐述。

    Abstract:

    Abstract:Hypopharyngeal malignant tumors account for approximately 5%of head and neck malignancies. The primary tumor sites of hypopharyngeal carcinoma are piriform sinus (70%), posterior hypopharyngeal wall(15-20%)and postcricoid region(10-15%). The treatment strategy of hypopharyngeal carcinoma includes radiotherapy, chemotherapy, surgery andtheir combinations. A comprehensive treatment based on surgery is still the first treatment choice. The surgical technique falls into open surgery and minimally invasive surgery. The former consists of laryngeal preserving surgery and reconstruction, and total laryngectomy followed by reconstruction surgery of hypopharyngoesophagus. The latter consists of transoral CO2 laser microsurgery and transoral robotassisted resection of hypopharyngeal carcinoma. There is a rich lymphatic drainage in hypopharynx, thus lymph node metastasis is common.About 50% of the patients have cervical lymph node metastasis when they are diagnosed. The management of cervical lymph nodes is critical for patients’ prognosis. This article reviews the progress of surgical treatment forhypopharyngeal carcinoma based on literature and our clinical experience.

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引用本文

刘良发,董研博.下咽癌的外科治疗进展[J].中国耳鼻咽喉颅底外科杂志,2017,23(3):189-195

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  • 在线发布日期: 2017-06-30
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