Abstract:ObjectiveTo study the flora distribution and the resistance to antibiotics of pathogenic bacteria in chronic suppurative otitis media for instruction of clinical medication.MethodsMiddle ear secretions from 163 cases with chronic suppurative otitis media were cultured for bacteria and fungi respectively. Antimicrobial sensitivity tests were also performed.Results136 strains pathogenic bacteria were isolated from the secretions with a detection rate of 83.4%(136/163). The main pathogenic bacteria were staphylococcus aureus (42 strains), pseudomonas aeruginosa (29 strains), Klebsiella pneumoniae (22 strains) and fungus (6 strains).ConclusionsStaphylococcus aureus is the main pathogen of chronic suppurative otitis media. There are great differences in resistances among different pathogens. In the clinical treatment of chronic suppurative otitis media, bacterial culture and antimicrobial sensitivity test should be performed, and sensitive antibiotics should be chosen according to the results.