ObjectiveTo provide references for the diagnosis and treatment of otogenic intracranial thrombophlebitis via summarizing its clinical characteristics.MethodsClinical data of 8 patients suffering from otogenic intracranial thrombophlebitis admitted to our hospital between Jan 2010 and March 2017 were analyzed retrospectively. Of them, 5 were male and 3 were female. As for the etiology, the otogenic intracranial thrombophlebitis was caused by chronic suppurative otitis media in 7 and mastoid surgery in one. All the patients received comprehensive management according to “Chinese guideline for diagnosis and treatment of cerebral venous thrombosis (2015 edition)”. ResultsAfter regular treatment according to the guideline for 3 to 8 months, clinical symptoms were relieved completely in all patients, and imaging examination revealed recanalization or shrinked filling defect size of the occluded sinus. Followup showed no sequelae of nerve system.ConclusionThe diagnosis of otogenic intracranial thrombophlebitis depends upon medical and surgical history, clinical symptoms as well as relevant auxiliary examination. Once diagnosed, the primary disease should be managed promptly, combined with standard anticoagulant treatment, thrombolytic therapy, control of intracranial pressure and nerve protection.