ObjectiveTo investigate the differences of voice parameters between patients with mutational falsetto and normal males.Methods30 patients with mutational falseto (patient group) and 30 normal males (normal group) were included in this study. Their voice parameters were obtained with dynamic laryngoscopy and analyzed comparatively. ResultsDynamic laryngoscopy showed incomplete glottic closure in 26 (86.67%, 26/30) patients. The average fundamental frequency (F0) of the patient group was (243.3±42.1) Hz, which was much higher than that of the normal group ［(146.2±25.4)Hz］ (P<0.01). The average pronunciation loudness of the patient group was (80.0±8.3) dBA while that of the normal group was (82.2±9.1) dBA, and the difference was statistically insignificant (P>0.05). Their differences of both shimmer ［(2.6±1.4)% vs (1.9±0.7)%］ and jitter ［(0.5±0.2)% vs (0.6±0.2) %］ were statistically insignificant (both P>0.05). The voice handicap index (VHI) in the patient group was -0.5±1.6, which was significantly lower than that in the normal group (3.8±1.6) (P<0.01). The maximum phonation time (MPT) of the patient group was (16.0±7.5)s, which was much shorter than that of the normal group (32.0±4.9)s (P<0.01). The range in the patient group was (288.4±140.8)Hz, which was much lower than that in the normal group ［(611.1±226.1)Hz］ (P<0.01).ConclusionsCompared with normal males, most patients of mutational falsetto may have incomplete glottic closure with higher F0, lower VHI, shorter MPT and narrower range. However, their pronunciation loudness, shimmer and jitter are similar to normal.