ObjectiveTo provide evidence for the frontal sinus anatomy classification (FSAC) and classification of the endoscopic frontal sinus surgery (EFSS) via exploring radiological anatomic features of the position relationship between frontal sinus drainage pathway (FSDP) and frontoethmoidal cells.MethodsThe computed tomography (CT) data (including reconstructed coronal，sagittal and axial imagines with slice thickness of 1 mm) of nasal sinuses from 100 outpatients were analyzed retrospectively. According to the International Frontal Sinus Anatomy Classification (IFAC) and Classification of the Extent of Endoscopic Frontal Sinus surgery(EEFSS) (Wormald, 2016), the radiological anatomic features of position relationship between FSDP and frontoethmoidal cells were explored and occurrence rates of all kinds of frontoethmoidal cells were detected. ResultsAccording to IFAC and the CT imaging relationship between the FSDP and the frontoethomidal cells, all the frontoethomidal cells were classified as three groups: anterior cells of FSDP (including agger nasal cell, supra agger cell and supra agger frontal cell), posterior cells of the FSDP (including supra bulla cell, supra bulla frontal cell and supraorbital ethmoid cell) and medial cells of the FSDP (frontal septal cell). The occurrence rates of these cells were 96% (agger nasal cell), 40% (supra agger cell) , 24% (supra agger frontal cell), 46% (supra bulla cell),13% (supra bulla frontal cell) and 8% (supraorbital ethmoid cell) and 30% (frontal septal cell) respectively.ConclusionClassification of the frontoethomidal cells based on the threedimensional reconstruction of CT has clinical guiding significance for the classification of the endoscopic frontal sinus surgery.