ObjectiveTo investigate the causes and treatment strategies of nasopharyngeal hemorrhage after radiotherapy for nasopharyngeal carcinoma(NPC).MethodsA retrospective analysis of 25 patients with nasopharyngeal hemorrhage hospitalized after radiotherapy in our hospital from January 2012 to December 2017 was performed. The main treatments included filling up nasal nasopharyngeal, endoscopic nasopharyngeal molting and necrotic granulation debridement, interventional therapy, coblator surgery, nasal endoscopic resection of nasopharyngeal tumor.ResultsOf the 25 patients, nasopharyngeal hemorrhage was caused by the recurrence of NPC in 8 cases, 3 of which died of massive hemorrhage; 5 cases were caused by pseudoaneurysm, 3 of which died of massive hemorrhage, 2 of which were rescued due to interventional therapy for hemostasis;11 cases resulted from the granulation bleeding after the radiotherapy of NPC. Among them, 7 cases were successfully hemostasis by coblator surgery, 3 cases stopped bleeding after intervention, 1 case was stopped by hemostasis,1 case was died from massive bleeding.ConclusionsThe complication of nasopharyngeal hemorrhage after radiotherapy for NPC has a high mortality rate. The NPC recurrence and pseudoaneurysm are the most dangerous. It can effectively reduce the mortality of bleeding after radiotherapy of NPC by actively examination to confirm the cause of bleeding and treatment for the cause of bleeding.