Abstract:ObjectiveTo study the effect of adjustable titanium partial ossicular replacement prosthesis (PORP) in type II tympanoplasty.MethodsClinical data of 95 chronic suppurative otitis media patients received radical mastoidectomy combined with type II tympanoplasty with adjustable titanium PORP (experimental group, n=47) or fixed titanium PORP (control group, n=48) were analyzed retrospectively. The audiometric changes ［airbone gap (ABG) at 0.5,1,2,4kHz］ and effective rate at 3 months and one year after surgery were compared.Results①45 cases in the experimental group succeeded in onestage surgery with a successful rate of 95.7% (45/47) (2 failure cases included one with PORP displacement and one with fascia fissure). 44 cases in the control group succeeded with a successful rate of 91.7%（44/48）(Failure cases included 2 with PORP displacement and 2 with fascia fissure). A total of 89 cases had audiometric data available for analysis. ②The difference of ABG between the two groups at 3 months was statistically significant (P<0.05), but insignificant (P>0.05) at one year postoperatively.③The effective rate between the two groups was statistically insignificant (P>0.05).ConclusionsAdjustable titanium PORP can provide hearing outcomes superior to fixed one at 3 months after ossiculoplasty. It can be selected in clinic to improve the function of middle ear transmission. Keywords: