ObjectiveTo explore the therapeutic effect of a combined lipidlowering therapy on sudden hearing loss patients with hyperlipidemia.MethodsIt was analyzed retrospectively for the clinical data of 181 patients diagnosed with sudden hearing loss and hyperlipidemia who were hospitalized from 2017 to 2019. The differences of the average hearing threshold (Pure Tone Audiometry, PTA), and the total effective rate was compared before and after treatment in the group with combined lipidlowering therapy and the group without lipidlowering therapy.ResultsThe differences of the PTA before and after treatment were (24.8±14.3)dB and (19.6±13.2)dB, respectively. And the total effective rates were 67.1% and 52.1% respectively. The differences between the two groups were statistically significant (all P＜0.05).ConclusionThe combined lipidlowering therapy can significantly improve the hearing recovery of sudden hearing loss patients with hyperlipidemia. For the patients without obvious treatment contraindications, after fully communicating with them and obtaining the understanding and consent from the patients, the combination of lipidlowering therapy can be tried to improve the prognosis.