Abstract:ObjectiveTo study the longterm efficacy and related influencing factors in patients with laryngeal cancer after surgery.MethodsThe clinical data of 325 patients with laryngeal cancer were collected and analyzed by a retrospective study. The patients were admitted to Department of Otolaryngology Head and Neck Surgery, First Clinical Medical College, Shanxi Medical University from January 2007 to July 2016, including 296 males and 29 females. The ratio of male to female was 10.21∶1. The average age was (62±9.84) years.ResultsThe overall 5year survival rate, diseasespecific survival rate, and diseasefree survival rate of the cumulative survival curve were 75.4%, 78.2%, and 71.2%, respectively. Univariate analysis showed that there were significant differences between groups for the survival distribution of all clinical factors, including age, clinical stage, T grade, lymph node metastasis, recurrence, and surgical approach (P<0.05). Multivariate analysis showed that age, recurrence, and clinical stage significantly reduced the survival rate (P<0.05).ConclusionsThe 5year survival rate of laryngeal cancer patients is high postoperative, and the first choice of surgical treatment is feasible. Recurrence, clinical stage and old age are independent risk factors for postoperative survival of patients with laryngeal cancer.