Abstract:ObjectiveTo investigate the survival and prognostic factors of patients with laryngeal carcinoma after surgical treatment.MethodsClinical data of 174 patients with laryngeal carcinoma surgically treated in Shanghai Changzheng Hospital from 2010 to 2014 were analyzed retrospectively. Of them, 164 were male and 10 were female. Their age ranged from 35 to 87 years old with an average of (60.73±9.88). To determine the independent prognostic factors of laryngeal carcinoma patients, the single factor analysis was conducted by Kaplan Meier module, and the multiple factor analysis was conducted by Cox proportional risk model.ResultsThe overall 5year survival rate was 64.4% and that of the early stage patients (T1 and T2) was 77%. Univariate analyses showed that clinical stage, pathological differentiation, complications, T stage and N stage, operation mode, neck lymph node dissection, primary site of tumor were related to the 5year survival rate. Cox multivariate analyses showed that T stage, N stage were independent risk factors for prognosis of laryngeal carcinoma.ConclusionT stage, N stage, degree of pathological differentiation and complications are independent factors affecting the survival rate of patients with laryngeal carcinoma.