ObjectiveTo investigate the arytenoid cartilage calcification on the therapeutic effect of laryngeal contact granuloma in male patients.MethodsClinical data of 115 male patients with laryngeal contact granuloma were analyzed retrospectively, and the effect of arytenoid cartilage calcification on the therapeutic outcome was analyzed.ResultsThe patients’ age ranged from 22 to 68 years old with an average of 45.82. Of them, the granuloma was unilateral in 110 cases (95.65 %, 110/115) and bilateral in 5 (4.35%, 5/115). As for the etiology, 67 cases had a history of laryngopharyngeal reflux (58.26%, 67/115), 5 cases were induced by endotracheal intubation (5/115%, 4.35%), and the rest had no apparent causes. Laryngeal computed tomography (CT) of all the cases confirmed arytenoid cartilage calcification in 102 (88.70%, 102/115). Among the 102 cases with arytenoid cartilage calcification, the case number with cure time > 3 months was 68, and that ≤3 months was 34. Of the 13 patients without calcification, the case numbers were 4 and 9 respectively. The percentage of patients with cure time ＞3 months in arytenoid cartilage calcification group was significantly higher than that in the group without calcification (χ2=4.906, P=0.027).ConclusionThe reason for long treatment time of the laryngeal contact granuloma patients with arytenoid cartilage calcification may be the arytenoid cartilage calcification caused by chronic inflammatory stimulation with relatively long course of disease and difficulty in treatment.