Objective To investigate the efficacy of precise vestibular stimulation training to the subjects with motion sickness(MS). Methods A total of 62 outpatient patients with motion sickness in outpatient department were collected. All the subjects took the same bus within 2 weeks before the training,and the symptoms of motion sickness were self-rated by visual analogue scale (VAS) after 30min on bus. All subjects received 3 times of precise vestibular stimulation training,1 week after stimulation training, they took the same bus again, and then the severity of motion sickness symptoms self-scored by the VAS once more.The scores of motion sickness symptoms of the patients were compared for different groups before and after treatment to evaluate the therapeutic effect of accurate vestibular rehabilitation treatment on motion sickness. Results The scores of all subjects 1 week after precise vestibular stimulation training were significantly lower than those before training (8.18±4.67 vs 27.67±7.16, P<0.05),The training effect of the group with severe symptoms and extremely severe symptoms were better than that of the group with moderate symptoms(χ²=21.98,P<0.05). There was no significant difference between male and female subjects(χ²=0.008,P>0.05). The training effect of youth group was better than that of mid-aged group(χ²=5.57,P<0.05). Conclusions Precise vestibular stimulation training has obvious therapeutic effect to subjects with motion sickness, which can reduce the sensitivity of motion sickness. The training effect of the severe group and extremely severe group were better than that of the moderate group.