Objective To analyze the clinical characteristics and prognosis of uremia patients with sudden deafness. Methods Twenty-nine patients (30 ears) were collected, who had uremia complicated sudden deafness treated in Huili County People's Hospital from January 2015 to December 2019. The average threshold of initial hearing in the 29 patients were (62.33±13.68) dB HL. And 17 ears (56.67%) of the 30 ears were accompanied with tinnitus, 8 ears (26.67%) of the 30 ears were accompanied with vertigo;9 ears (30.00%) of the 30 ears exhibited flat-type hearing loss and 13ears (43.33%) of the 30 ears were completely deaf. According to the duration of uremia, the 29 patients were divided into <2 years group (13 cases, 13 ears), 2~4 years group (8 cases, 8 ears) and 4 years group (8 cases, 9 ears). And the hearing recovery was compared among three groups. Results Three months after the end of treatment for the 29 patients(30 ears), 3 ears (10.00%) were cured, 5 ears (16.67%) were significantly effective, 6 ears (20.00%) were effective, and 16 ears (53.33%) were ineffective. The average improvement of hearing threshold was (15.68±7.43) dB HL. There were no significant differences in cure rate, significant efficiency, effective rate and inefficiency in <2 years group, 2~4 years group and 4 years group according to the duration of uremia. The improvement of hearing threshold in the three groups was (20.52±7.95), (16.30±6.27) and (7.78±9.36) dB HL, respectively, and the difference between groups was statistically significant (P<0.05). Conclusion Patients with uremia complicated with sudden deafness often suffer from severe hearing loss, and the hearing recovery is poor. The longer the course of uremia, the worse the prognosis.