Objective To investigate the characteristics of allergens in patients with allergic rhinitis (AR) in Liaoyang area.Methods Serum specific IgE (sIgE) was detected in 408 AR patients in Liaoyang area by the method of in vitro specific allergen detection.Results ①Serum samples from 408 AR patients were detected. The top six allergens in order of the positive rate were ambrosia/artemisia/humulus (39.71%), house dust mite (37.30%),rosa/dianqing/branch/cross chain/aspergillus niger (24.26%), juniper/birch (21.81%), egg white (13.00%), and mulberry (12.75%); ②The total positive rate of sIgE for the inhalation allergen was 86.7% (354/408) and that for the ingestion allergen was 27.2% (111/408); ③Patients with single positive allergen accounted for 26.23% (107/408), 2 kinds of positive allergens accounted for 53.68% (219/408), 3 kinds accounted for 10.29% (42/408), and 4 or more kinds accounted for 9.80% (40/408); ④The top three allergens in AR patients with single positive allergen were dwarf ragweed/Artemisia/Humulus (25/107), rosa/dianqing/branch/cross chain/aspergillus niger (21/107), house dust mite (15/107). The top three allergen combinations in AR patients with 2 kinds of positive allergens were dwarf ragweed/Artemisia/humulus and house dust mite (19/219), rosa/dianqing/branch/chain/aspergillus niger and house dust mite (18/219), rosa/dianqing/branch/cross chain/aspergillus niger and dwarf ragweed/artemisia/humulus (16/219).Conclusion Pollen of porpoise and other plants, dust mites and molds are the most predominant allergens in AR patients in Liaoyang area.