Objective To evaluate the application of LigaSure small jaw in superficial or total parotidectomy for parotid tumors.Methods This was a prospective study on 47 patients undergoing superficial or total parotidectomy for parotid tumors in the Hospital of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Xi’an Jiaotong University from Jan 2016 to Dec 2018. All the patients were divided into two groups: 27 patients in group A had LigaSure small jaw parotidectomy, and 20 in group B had conventional parotidectomy. The operation time, amount of bleeding, volume of drainage within 48 hours after surgery and postoperative complications between the two groups were assessed and compared.Results Operation time was significantly shorter in group A (85.56±43.94)min than in group B (123.00±44.14)min (P<0.05). Group A was associated with a significant reduction in intraoperative blood loss (46.67±42.34)mL vs (75.00±49.92)mL(P< 0.05). The different amount of postoperative drainage (38.15±17.16)mL vs (63.25±21.59)mL(P<0.05) was noted between the two groups. No significant differences were observed between group A and B with respect to complications. Use of LigaSure in superficial parotidectomy compared to conventional surgery was associated with a significant reduction in intraoperative blood loss (33.81±21.79)mL vs (54.67±19.32)mL, operation time (70.00±17.54)min vs (104.00±25.58)min and the amount of postoperative drainage (32.62±11.36)mL vs (54.33±8.84)mL. In patients undergoing total parotidectomy, no significant differences of parameters were observed between the two groups.Conclusion Use of the LigaSure in the surgical treatment of parotid tumors is safe, and has some advantages over conventional methods in operation time, intraoperative blood loss and postoperative drainage, especially in superficial parotidectomy.