Nasal bleeding is one of the most common diseases in the otorhinolaryngology emergencies. It is of great significance and challenge to otolaryngologist for rapid and accurate localization of epistaxis. It is very important and conducive to the treatment of epistaxis for rhinology specialists by mastering the common sites of primary epistaxis and familiar with the distribution characteristics of the arteries of the nasal cavity. This article reviewed the classification of epistaxis, the blood supply of the nasal cavity, the common sites with the affiliated vessels and the treatment of primary epistaxis. It is of great significance to study of the blood supply of the nasal cavity and and identify common bleeding sites and supplying vessels for finding bleeding points, thereby effectively treating primary epistaxis.