Abstract:Objective The aim of this study is to analyze the proportion of endolymphatic hydrops (EH) in patients with Meniere's disease (MD) verified by 3D-FLAIR MRI through intravenous gadolinium (IV-Gd) and to explore its clinical diagnostic value for MD. Methods Selected from March 2016 to October 2021 in our hospital, 86 patients with suspected MD according to clinical symptoms, all of them underwent inner ear 3D -FLAIR MRI scan through IV-Gd, the clinical characteristics and EH results were compared and analyzed. Results Among the 86 patients with suspected MD, There are 32 males and 54 females, aged 28 to 72 years ald, with an average age of 51.7±11.2 years, and a medical history of 1month to 18 years, with an average of 2.9 ± 2.6 years. 61 suspected MD patients showed EH in inner ear IV-Gd (set as EH-positive), 56 of them were confirmed MD, and the remaining 25 suspected MD patients showed no obvious EH in inner ear IV-Gd (set as EH negative), of which 7 A patient was diagnosed with MD.. Among the 61 cases of EH positive, 23 cases (37.7%) had both ears EH Positive,and among the 84 EH positive ears, 29 ears (34.5%) had vestibular EH, 15 ears (17.9%) had cochlear EH, and 33ears (75%) had both vestibular and cochlear EH. IV-Gd diagnosis of MD The sensitivity, specificity, accuracy, the positive and negative predictive values were 88.9%, 78.3%, 86.1%, 91.8%, and 78.3%, respectively, and the area under the ROC curve was 0.836; the IV-Gd had a good consistency with the clinical diagnosis result (Kappa=0.653 P <0.001). Comparison of EH-positive and EH-negative groups of MD patients, There was no statistical significance in age, gender, migraine complicated and MD stage between the EH-positive and EH-negative groups of MD patients (P>0.05). The clinical course of MD and average PTA were statistical significance (P<0.05). Conclusion With the help of the EH results detected by IV-Gd can effectively improve, the confirm diagnosis rate of MD. The course of MD and hearing loss may be related to EH. If possible, IV-Gd may be used for further corroboration in patients with suspected MD.