Abstract:Allergic Rhinitis (AR) is a non-infectious chronic inflammatory disease of nasal mucosa mediated by specific immunoglobulin E(Ig E), in which Th2 and its secreted IL-4 and IL-5 are involved in the main inflammatory process. B lymphocyte-inducible maturation protein-1 (Blimp-1) is a transcription inhibitor containing zinc finger motifs. Blimp-1 regulates the development, differentiation and function of T cells. Blimp-1 plays an important role in regulating the proliferation and differentiation of activated T lymphocytes and immune homeostasis. Blimp-1 plays an important role in regulating the proliferation and differentiation of activated T lymphocytes and immune self-stabilization. It is of great significance to explore the possible role of Blimp-1 in the occurrence and development of AR for the anti-inflammatory effects of Blimp-1 on the lower respiratory tract and other allergic inflammatory response diseases. It is great value for studying blimp-1 related to the pathogenesis, new treatment methods, improvement of symptoms and reduction of complications of AR. Therefore, this paper reviews the role of Blimp-1 in the pathogenesis of AR and its research progress.