Objective To investigate the impact of nasal septal deviation (NSD) on the position of middle turbinate (MT) and its clinical.Methods Imaging data of paranasal sinus computed tomography (CT) in 100 patients with NSD underwent septoplasty combined with turbinate surgery from Feb 2018 to Dec 2019 were investigated retrospectively. GE Medical Image System (Centricity Enterprise Web 3) was adopted to measure the degree of NSD and the concave and convex structure parameters of MT. The correlation between MT index and the degree of NSD was analyzed.Results The width of MT on the convex side (4.56±1.55) mm was smaller than that on the concave side (7.01±1.75) mm (P<0.01). The distance between the MT and the midline on the convex side (5.04±1.37) mm was significantly larger than that on the concave side (1.48±1.50) mm (P<0.01). The NSD degree showed a positive correlation with the width of MT on the concave side (r=0.245, P<0.05) and a negative correlation on the convex side (r=-0.420, P<0.01). The correlation of the NSD degree with distance between MT and the midline was negative on the concave side (r=-0.430, P<0.01) and positive on the convex side (r=0.549, P<0.01).Conclusions In patients with NSD, there are MT compensatory hypertrophy in concave side and shift to the midline, and the adaptability of MT on convex side is reduced and away from the midline. The hypertrophic MT including concha bullosa should be paid attention to in septoplasty.