Abstract:Objective To analyze the characteristics of nystagmus and the clinical efficacy in patients diagnosed with light cupula.Methods A total of 42 patients diagnosed with light cupula were selected as the research subjects,who were enrolled in the vertigo clinic of the Department of Otolaryngology-Head and Neck surgery, the First People's Hospital of JinZhong from January 2018 to January 2021. The characteristics of nystagmus were recorded and analyzed by video electronystagmus. All patients were treated with Barbecue roll maneuver and oral drug after reduction, and the efficacy was evaluated immediately,one week and one month later.Results There were 42 patients with light cupula, of which two cases (4.8%) were secondary to sudden deafness. All of the patients,spontaneous nystagmus was appeared in upright position at 10 case(23.8%) and in supine position at 24 cases (57.1%), which were oriented to the healthy side and appeared in the second zero plane of nystagmus disappearance located on the affected side. All patients presented persistent geostatic positional nystagmus in bilateral head turning position, with an average duration of > 1min and an average slow phase velocity (SPV) of > 20°/s, and no obvious incubation period. After treatment, 0 cases were cured immediately, 5 cases(11.9%) were improved and 37 cases(88.1%) were invalid. After one week, 2 cases (4.8%) were cured, 18 cases (42.9%) were improved, and 22 cases (52.4%) were invalid. After 1 month, 39 cases (92.9%) were cured, 3 cases (7.1%) were improved, and 0 cases were invalid. There was statistically significant difference in the effectafter treatment immediately,one week later and one month later(P<0.05). Age was correlated with immediate curative effect (P<0.05). The intensity of nystagmus on the affected side may be correlated with the curative effect one week later (P<0.05).The intensity and duration of nystagmus on the affected side were correlated with the curative effect after 1 month (P<0.05).Conclusions Nystagmus with light cupula is characterized by persistent geotropism, long duration and no incubation period. In some cases, zero plane may occur in partial patient accompanied by supine nystagmus. The disease has a certain self-healing and good prognosis. Age, intensity and duration of nystagmus on affected side have influence on the prognosis of patients. There were relatively better efficacy of treatment in young patients with weak intensity of nystagmus and short duration of nystagmus.