The 3D printing technology has been widely used in the field of biomedicine in recent years. Although the application research of 3D printing technology was rarely reported in the field of nasal-skull base surgery, the 3D printing technology has a broad application prospect with its advantages of rapid prototyping and three-dimensional physical reproduction. Its clinical application mainly involves repair of nasal-skull base defect, preoperative planning and preoperative operation simulation, anatomy teaching and training, patient education etc. This article provided an overview of the development status of 3D printing technology in the field of nose-cranial base surgery. Meanwhile, the development prospect of 3D printing technology was prospected.