Objective: Factors associated with hypoxemia in tracheobronchial foreign body removal in children under rigid bronchoscopy under general anesthesia. Method: The clinical data of 432 children with tracheobronchial foreign bodies under general anesthesia were retrospectively studied, and the correlation between the degree of intraoperative hypoxemia and age, the position of foreign body stay, the time of foreign body stay and preoperative pulmonary complications was analyzed. Result: There was no correlation between the occurrence of mild and moderate intraoperative hypoxemia and age, foreign body stay position, foreign body stay time and preoperative pulmonary complications (P>0.05), but there was a correlation between age, foreign body stay position, foreign body stay time and preoperative pulmonary complications and severe intraoperative hypoxemia. Conclusion: Age, location of foreign body stay, length of foreign body stay and preoperative pulmonary complications were correlated with the occurrence of severe intraoperative hypoxemia.