目的 分析新疆地区变应性鼻炎(AR)儿童常见变应原的分布,为该区AR患儿流行病学研究及诊治提供参考依据。方法 自2017年1月至2021年6月我院就诊的,并具有典型AR症状及体征的566例AR患儿纳入研究,将血清特异性变应原(sIgE)结果,就诊时间,不同年龄段及性别等进行分析。结果 425例(75.1%)AR患儿至少一种变应原阳性,吸入性变应原主要致敏因素,艾蒿、屋尘螨、粉尘螨、柳树、屋尘是最常见的5种吸入性变应原。居前5位的食入性变应原分别为：牛奶、小麦面粉、鸡蛋、花生、牛肉。在不同年龄组AR患儿中,艾蒿、柳树、豚草三种吸入性变应原,食入性变应原中,牛奶阳性率具有统计学差异(P＜0.017),男性变应原阳性率略高于女性(P＞0.05),在男性中屋尘阳性率明显高于女性,女性中羊肉阳性率高于男性(P＜0.05)。结论 新疆地区AR患儿变应原以吸入性变应原阳性居多,不同季节变应原分布,在不同年龄段、不同性别中变应原存在部分差异。
Objective To analyze the distribution of common allergens in children with allergic rhinitis (AR) in Xinjiang, to provide reference for epidemiological research, diagnosis and treatment of children with AR in this area. Methods From January 2017 to June 2021, 566 children with AR with typical symptoms and signs were enrolled in the study. Serum specific allergen (sIgE) . Results Visit time, different age and gender groups analyzed. Results: 425 cases (75.1%) of AR children were positive for at least one allergen. Inhaled allergens were the main sensitizers. Mugwort, house dust mites, dust mites, willows, and house dust were the five most common inhalations allergens. The top 5 ingestible allergens are: milk, wheat flour, eggs, peanuts, and beef. Among children with AR in different age groups, there are three inhaled allergens of mugwort, willow, and ragweed. Among the ingested allergens, the positive rate of milk is statistically different (P<0.017), and male allergens are positive The rate is slightly higher than that of women (P>0.05), the positive rate of house dust in men is significantly higher than that of women, and the positive rate of lamb in women is higher than that in men (P<0.05). Conclusion Most allergens in children with AR in Xinjiang are positive for inhaled allergens. The distribution of allergens in different seasons is different. There are some differences in allergens in different age groups and different genders.