奥密克戎变异株感染患者合并咽痛临床表现及特征分析
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1.上海中医药大学附属曙光医院 耳鼻喉科;2.上海中医药大学附属曙光医院 耳鼻咽喉头颈外科;3.上海中医药大学附属曙光医院 感染科

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国家自然科学基金项目(面上项目,重点项目,重大项目)


Clinical manifestations and characteristics of patients infected with omicron variant strain complicated with pharyngeal pain
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    摘要:

    目的 观察奥密克戎变异株(SARS-CoV-2 Omicron)患者咽痛临床表现及特征分析。方法 收集2022年4月18日-2022年5月30日上海市中医药大学附属曙光医院西院定点医院感染一科一病区142例Omicron变异株感染患者的病例资料,根据咽痛程度分级评分、咽痛出现时间、咽痛持续时间、咽痛引起的心理状况、咽痛消失后咽部不适症状持续时间等情况,分析临床特点。结果 在纳入的142例Omicron变异株感染患者中轻型111例(78.2%)、普通型例27例(19.0%)、重型4例(2.8%);各组间咽痛程度分级、咽痛出现时间差异均无统计学意义(P>0.05);重型组咽痛持续时间、咽痛消失后咽部不适症状持续时间明显延长,与轻型组和普通型组比较均有显著性差异(P<0.05),普通型组咽痛持续时间最短,与轻型组比较有显著性差异(P<0.05);在疼痛引起的心理状况观察中轻型组较严重,与其他两组比较差异有统计学意义(P<0.05)。结论 Omicron变异株感染患者的临床症状中咽痛较为明显,且影响患者发病期间生活质量、营养饮食和疾病康复,因此临床医师不能忽视Omicron变异株感染患者咽痛的治疗和改善。

    Abstract:

    Objective To observe the clinical manifestations and characteristics of pharyngeal pain in patients with SARS-COV-2 Omicron variant strain.Methods The clinical data of 142 patients infected with omicron variant strain were collected from April 18, 2022 to May 30, 2022, in the first ward, First Department of Infection,Shuguang Hospital affiliated to Shanghai University of Chinese Medicine. The clinical characteristics were analyzed according to the grading score of pharyngeal pain, the occurrence time of pharyngeal pain, the duration of pharyngeal pain, the psychological status caused by pharyngeal pain, and the duration of pharyngeal discomfort symptoms after the disappearance of pharyngeal pain.Results Among 142 patients infected with omicron variant strain, 111 cases (78.2%) were mild, 27 cases (19.0%) were common, and 4 cases (2.8%) were severe. There were no significant differences in the occurrence time and grade of pharyngeal pain among all groups (P>0.05). The duration of pharyngeal pain and the duration of pharyngeal discomfort symptoms after the disappearance of pharyngeal pain in the severe group were significantly prolonged, and there were significant differences compared with the mild group and the ordinary group (P<0.05). The duration of pharyngeal pain in the ordinary group was the shortest, and there were significant differences compared with the mild group (P<0.05). The psychological status caused by pain was more serious in the mild group, and the difference was statistically significant compared with the other two groups (P<0.05).Conclusions The pharyngeal pain of patients infected with omicron variant strain is obvious, and affects the quality of life, nutritional diet and disease rehabilitation of patients during the onset, so clinicians should not ignore the treatment and improvement of pharyngeal pain in patients infected with Omicron variant strain.

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  • 收稿日期:2022-06-08
  • 最后修改日期:2022-06-29
  • 录用日期:2022-07-05
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