鼻腔鼻窦腺样囊性癌的临床及手术疗效分析
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1.云南省第三人民医院;2.The Third People'3.'4.s Hospital of Yunnan Province

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云南省科技厅地方高校联合专项202001BA070001-079


Clinical and surgical efficacy analysis of sinus adenoid cystic carcinoma of the nasal cavity
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1.The Third People'2.'3.s Hospital of Yunnan Province

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    []目的: 探讨鼻腔鼻窦腺样囊性癌的临床特点及手术疗效分析。方法:回顾性分析云南省第三人民医院2010年6月~2017年 6月收治的31例病理确诊为鼻腔鼻窦腺样囊性癌的患者主要临床表现及生物学特性,针对不同部位、分期患者进行不同方式的手术及术后放疗。结果: 31例患者随访30例,1例失访,3年内4例死亡(生存率87.1%),5年生存率为70.9%,3年局部复发5例(复发率16.2%),5年复发率为25.8%。结论:鼻腔鼻窦腺样囊性癌生长部位深在,毗邻结构复杂,肿瘤的高侵袭性和沿着神经浸润生长的习性,手术彻底切除干净较难,易复发。传统手术结合鼻内镜颅底技术以及神经追踪技术是减少复发、提高生存率的有效方法。

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    Abstract :Objectiv To explore the clinical features and surgical efficacy of nasal sinus adenoid cystic carcinoma. Methods The main clinical manifestations and biological characteristics of 31 patients with pathologically confirmed nasal sinus adenoid cystic carcinoma admitted from June 2010 to June 2017 in the Third People's Hospital of Yunnan Province were retrospectively analyzed, and different methods of surgery and postoperative radiotherapy were carried out for patients with different parts and stages.Results After 31 patients were followed up and one was lost to follow-up, four patients died within 3 years (survival rate was 87.1%) ,The 5-year survival rate was 70.9%.5 patients had local recurrence (recurrence rate16.2%), and a 5-year recurrence rate was 25.8%. Conclusion Nasal sinus adenoid cystic carcinoma growth site is deep, adjacent to the complex structure, tumor high invasion and along the nerve infiltration growth habit. remove tumor completely and clean by surgery is difficult, easy to recur, traditional surgery combined with nasal endoscopic skull base technology and nerve tracking technology is an effective way to reduce recurrence and improve survival rate.

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  • 收稿日期:2022-10-24
  • 最后修改日期:2022-11-19
  • 录用日期:2022-11-21
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