Allergic rhinitis (AR) is a common benign allergic disease induced by allergens in the body. In addition to the nasal and ocular symptoms associated with allergies, it can also lead to problems such as decreased sleep quality and daytime quality of life, affecting the patients’ work and life. At present, the treatment methods for AR are limited, mainly by stay away from allergens and drug control, and have their limitations and disadvantages in terms of efficacy. Nowadays, the application of stem cell therapy has been greatly developed in the treatment of various diseases. Adipose-derived mesenchymal stem cells have considerable potential in the treatment of AR due to their unique immunomodulatory and anti-inflammatory effects, as well as the advantages of convenient access.