【Abstract】 Objective: To investigate the relationship between nasal septum deviation and maxillary sinus pneumatization classification. Methods: A retrospective assessment was made for 100 patients with nasal septum deviation without coexisting sinonasal morbidity and compared to 60 healthy individuals. The images were observed using GE Light Speed 64 slice spiral CT, and the data were statistically processed using SPSS 22.0. The degree of maxillary sinus gasification was standardized by referring to the pneumatization classification of Liu Jinfeng et al, and the degree of nasal septum deviation was standardized by referring to the measurement method of Bhandary et al. To compare the relationship between nasal septum deviation and maxillary sinus gasification. Results: Septal deviations were right-sided in 54 % of the cases (n = 54) and left-sided in 46 % (n = 46). Deviation angles varied between 5.4° and 31.1°, with a mean value of 12.8° ± 4.1°. The gender distribution of patients with nasal septal deviation was statistically different from that of the control group (P<0.05), there was a statistically significant difference between sex and normal nasal septum maxillary sinus gasification (P< 0.05). There was a correlation between the Angle of nasal septum deviation in type I and type III maxillary sinuses (P<0.05). There was a significant relationship between nasal septum deviation and maxillary sinus gasification typing (P<0.05). Conclusions: Men are more likely to have nasal septum deviation and maxillary sinus hypergasification. The nasal septum deviation and the increase of the deviation Angle will affect the maxillary sinus gasification.