Objective To analyze the clinicopathological features of laryngeal carcinosarcoma and sarcomatoid carcinoma, and avoid missed diagnosis and misdiagnosis, so as to improve the level of diagnosis, treatment and prognosis of this disease.Methods Clinicopathological data, diagnosis and treatment process, as well as follow-up results of 6 cases of laryngeal carcinosarcoma and sarcomatoid carcinoma admitted to our hospital from July 2012 to Jan 2016 were analyzed retrospectively with literature review.Results All the 6 patients were surgically treated for the first time, and diagnosed as laryngeal carcinosarcoma or sarcomatoid carcinoma by routine postoperative pathological examination combined with immunohistochemistry. One of them underwent postoperative radiotherapy. During the follow-up period of 67 to 87 months, 4 of them relapsed and underwent reoperation. Four patients survived, one was lost to follow-up and one died.Conclusions Hoarseness is usually the first symptom of laryngeal carcinosarcoma or sarcomatoid carcinoma. With various morphological features and early smooth surface, they’re easy to be misdiagnosed as vocal cord polyp. Definite diagnosis depends upon routine pathological examination combined with immunohistochemistry. The main treatment is surgical resection, and extended resection is recommended, supplemented by postoperative radiotherapy. They are relatively easy to relapse after operation and the prognosis is generally good.