李欣1 吕芸2 张玥钰2 彭珍1 逯英杰1何健2
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1.甘肃中医药大学;2.甘肃省人民医院

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甘肃省人民医院国家级科研项目培育计划一般项目(19SYPYB-14)


Research progress on the relationship between serum vitamin E level and allergic rhinitis
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    摘要:

    变应性鼻炎(allergic rhinitis,AR)是由于辅助性T细胞(Th2)淋巴细胞过度活化而引起的一种鼻腔黏膜非感染性炎症型的疾病,是耳鼻喉科最常见的慢性难治性疾病。在过去6年中我国AR患病率从11.1%升高到17.6%,患病人数增加了1亿,由于患病率明显上升,越来越多的学者开始关注AR。维生素E在临床实践中被广泛用于预防和治疗不同的疾病,近年来有基础科学研究发现维生素E与变应性鼻炎有着重要的联系,它可以减少免疫过敏反应的发生。本文作者通过对维生素E的代谢、作用机制及其与变应性鼻炎之间的关系的最新研究进展进行综述。旨在为维生素E在变应性鼻炎中的应用提供一定的理论指导。

    Abstract:

    Allergic rhinitis (allergicrhinitis,AR) is a non-infectious inflammatory disease of nasal mucosa caused by excessive activation of helper T cells (Th2) lymphocytes. It is the most common chronic refractory disease in otorhinolaryngology. In the past six years, the prevalence rate of AR in China has increased from 11.1% to 17.6%, and the number of patients has increased by 100 million. Due to the obvious increase in the prevalence rate, more and more scholars have begun to pay attention to AR. Vitamin E is widely used in clinical practice to prevent and treat different diseases. in recent years, basic scientific studies have found that there is an important relationship between vitamin E and allergic rhinitis, which can reduce the occurrence of immune allergic reaction. The authors reviewed the latest research progress on the metabolism and mechanism of vitamin E and its relationship with allergic rhinitis. The purpose of this study is to provide some theoretical guidance for the application of vitamin E in allergic rhinitis.

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  • 收稿日期:2023-02-06
  • 最后修改日期:2023-03-13
  • 录用日期:2023-03-17
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