The change of airflow field caused by structural changes in nasal cavity and paranasal sinuses will affect the physiological function of nose, but it is always difficult to quantitatively study the airflow field in nasal cavity. The development of Computational Fluid Dynamics (CFD) provides a feasible way to study the changes of nasal airflow. There have been many achievements in the study of normal nasal physiological function, the analysis of airflow characteristics of abnormal nasal structure, the evaluation of surgical curative effect, virtual surgery and nasal drug research using CFD, which has obvious advantages. With the rapid development of computer technology and artificial intelligence, although facing many difficulties, CFD has great development potential in nasal clinical application.