分泌性中耳炎（secretory otitis media, SOM）是指以传导性聋及鼓室积液为主要特征的不伴有急性炎性表现的中耳积液的非化脓性中耳炎。其病因与生理机制复杂 ，以耳闷、耳鸣、耳痛等耳部症状为主，各年龄段均可发生，而学龄前儿童是高发人群。目前，分泌性中耳炎病因及发病机制尚未完全阐明，对SOM中耳积液的成分分析是研究SOM的病因及发病机制的常见方法，也是指导临床治疗的重要途径，本文通过对国内外发表的分泌性中耳炎中耳积液成分研究的相关文献阅读，对其研究进展进行比较总结。
Secretory otitis media (SOM) refers to non suppurative otitis media characterized by conductive hearing loss and tympanic effusion without acute inflammatory manifestations. Its etiology and physiological mechanisms are complex, with ear symptoms such as ear tightness, tinnitus, and earache being the main symptoms, which can occur in all age groups, and preschool children are the high-risk population. At present, the etiology and pathogenesis of secretory otitis media have not been fully elucidated. Analyzing the composition of ear effusion in SOM is a common method to study the etiology and pathogenesis of SOM, and is also an important way to guide clinical treatment. This article compares and summarizes the research progress of the composition of ear effusion in secretory otitis media published at home and abroad.