Early glottic laryngeal carcer is a common malignant tumor in otorhinolaryngology. When the tumor involves the anterior commissure, it may affect the recurrence and prognosis of patients. The disease is usually treated by radiotherapy, surgery and other clinical methods. In addition to conventional radiotherapy, radiotherapy strategies include segmented radiotherapy, intensity modulated radiotherapy, etc. Surgical treatment includes open surgery and minimally invasive surgery [transoral laser microsurgery, low-temperature plasma radiofrequency ablation (LTP-RFA), transoral robotic surgery]. At present, the optimal treatment mode in clinical practice is still controversial. Different modes of treatment have their advantages and disadvantages. In this paper describes a series of clinical treatment models for early glottic laryngeal carcinoma involving anterior commissure. It is expected to provide some reference for determining the best treatment mode.