Objective: To improve the understanding of intranasal glioma cell and reduce misdiagnosis. Methods: collected from 1 case of infants and young children intranasal glioma cell cases data, query and review the intranasal glioma cell related literature at home and abroad.Results: intranasal glioma cell main symptom is stuffy nose,gray-white translucent neoplasms were seen in the nasal cavity. Its more than seen in infants and young children, can accompany feeding difficulties, do not have familial transmissibility. With nasal polyps and bulging meningocele identify the disease, the main treatment is surgical resection, pathological diagnosis can be confirmed.Conclusions: In neonates or infants with persistent nasal obstruction and neoplasms , when meningoencephalocele is excluded, the possibility of intranasal glioma cell should be considered. Combined with medical history, perfect imaging and endoscopy and other related examinations, early surgery can avoid bone and craniofacial deformities and reduce the occurrence of postoperative complications.