川北医学院附属医院
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Department of Otolaryngology Head and Neck Surgery,Affiliated Hospital of North Sichuan Medical College
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目的:观察并讨论在耳内镜下使用人脱细胞异体真皮修补鼓膜的移植成功率和术后听力增益。方法:纳入2023年11月至2024年1月在我科行耳内镜下使用人脱细胞异体真皮修补鼓膜的患者28例,观察术后鼓膜穿孔愈合及听力改善情况。术前行乳突高分辨率CT扫描、耳内镜检查、纯音听阈测试及其他相关检查。术后半个、1个月、3个月随访复查,耳内镜检查观察鼓膜穿孔的愈合情况,纯音测听评估听力。采用SPSS 27 软件进行统计分析。结果:术后 3 个月,移植成功率达到 93% (26/28)。术前气导听力 41.61± 9.40dB HL 明显大于术后 3 个月 28.75±5.68dB HL (P=0.009)。总结:在耳内镜下使用人脱细胞异体真皮修补鼓膜穿孔是一种可靠的治疗方法,愈合率高、并发症少,听力恢复可。
Objective:To evaluate the graft success rate and postoperative hearing gain for tympanic membrane perforation? using Human-derived acellular dermal matrix under otoendoscope. Methods:A total of 28 patients who had received endoscopic myringoplasty without tympanomeatal flap elevation in our department from November? 2023 to January? 2024 were included. The recovery of tympanic membrane and hearing after surgery were examined using “before-after study in the same patient” design. Preoperative high-resolution computed tomography (HRCT) of temporal bone, endoscopic ear examination, pure tone audiometry and other routine examinations were performed. The outcomes included graft success evaluated by endoscopy and hearing gain evaluated by pure tone audiometry at 0.5,1 and 3 months after the surgery. The therapeutic efficiency was analyzed using SPSS software 27. Results: Three months after the surgery, the graft success rate achieved 93% (26/28). The preoperative air conduction hearing 41.61± 9.40dB HL was significantly greater than postoperatively 28.75±5.68dB HL at 3 months (P=0.009). Conclusion: Otoendoscopic repair of tympanic membrane perforation with Human-derived acellular dermal matrix as an implant material is a reliable treatment with few complications and good postoperative hearing recovery.
