显微技术在头颈部神经鞘瘤手术治疗中临床应用的回顾性调查研究
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湖南省肿瘤医院

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2024年度湖南省科学技术厅科普专项(2024ZK4141) ,2024年度湖南省自然科学基金项目(2024JJ9251), 2020年度湖南省肿瘤医院科研攀登计划国自培育项目(2020NSFC-B007),湖南省卫生健康委高层次卫生人才“225”工程,2019年中央补助医疗服务与保障能力提升(医疗卫生机构能力建设)项目。


Microsurgical Techniques in Head and Neck Schwannoma Surgery: A Retrospective Study
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    摘要:

    目的:头颈部神经鞘瘤较为少见,目前大样本的外科治疗经验有限。本研究拟通过回顾性分析手术治疗头颈部神经鞘瘤患者的临床资料,旨在为临床实践提供具有科学依据的参考,以优化治疗策略和提升治疗效果。方法:选取 2019 年 12 月至 2025 年 7月期间于湖南省肿瘤医院收治的头颈部神经鞘瘤患者作为研究对象,纳入研究的病例均符合以下条件:术前影像学检查提示头颈部占位;临床资料完整;术后病理确诊为神经鞘瘤。排除内镜治疗患者。本研究对神经鞘瘤患者的手术技巧、临床疗效及随访结果进行总结与分析。结果:87 例神经鞘瘤患者病灶均位于头颈部。所有患者手术均顺利完成,手术完整切除率达 100%。手术时间跨度为 27 分钟 - 460 分钟,术中出血量介于 20 - 500ml 之间。术后随访 8 - 66 个月,期间共发现 3 例患者出现复发情况,其中1例反复复发;另有 1 例患者继发肺癌,12 例(13.8%)患者出现神经损伤症状,在随访过程中,神经功能改善,无患者死亡。结论:神经鞘瘤术中采用显微技术可有效保留神经功能,并发症减少,结合术中神经电生理监测技术可提高手术安全性。

    Abstract:

    Objective: Schwannomas in the head and neck region are relatively rare, and there is limited large-sample surgical experience available. This study aims to retrospectively analyze the clinical data of patients who underwent surgical treatment for head and neck schwannomas, providing scientifically grounded references for clinical practice to optimize treatment strategies and improve therapeutic outcomes. Methods: Head and neck schwannomas treated at Hunan Cancer Hospital between December 2019 and July 2025 were selected as the study subjects. The included cases met the following criteria: preoperative imaging indicating a space-occupying lesion in the head and neck region, complete clinical data, and postoperative pathological confirmation of schwannoma. This study summarized and analyzed the surgical techniques, clinical efficacy, and follow-up results of these schwannoma patients. Patients who underwent endoscopic treatment were excluded. Results: All 87 schwannoma patients had lesions located in the head and neck region. All surgeries were successfully completed, with a 100% total resection rate. The operative duration ranged from 27 to 460 minutes, and intraoperative blood loss varied between 20 and 500 mL. During the follow-up period of 8 to 66 months, recurrence was observed in 3 patients, with 1 case experiencing repeated recurrence. Additionally, 1 patient developed secondary lung cancer, and 12 patients (13.8%) exhibited symptoms of nerve injury. Over the course of follow-up, these symptoms improved, and no patient deaths occurred. Conclusion: The use of microsurgical techniques during schwannoma surgery can effectively preserve nerve function and reduce complications. Combining intraoperative neurophysiological monitoring can enhance the safety of the surgery.

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  • 收稿日期:2025-07-02
  • 最后修改日期:2025-08-11
  • 录用日期:2025-08-15
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